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Using Artificial Intelligence to Identify Preventable Blindness

GLAICOMA uses artificial intelligence to improve the diagnosis of glaucoma by integrating OCT scans with clinical measurements such as RNFL thickness and vertical Cup-to-Disc Ratio (vCDR). Our deep learning model utilizes a bimodal approach, where each input stream is processed separately before combining the outputs in a fully connected layer. This late fusion technique enables the model to capture complex relationships between different types of data, resulting in a multi-class classification that distinguishes between normal, mild/moderate, and severe glaucoma cases.

To further enhance detection, we have developed a specialized deep learning algorithm focused on RNFL thickness maps. This algorithm is designed to differentiate glaucomatous from non-glaucomatous eyes by identifying subtle changes in the retinal nerve fiber layer, which is crucial for early detection and management of glaucoma. By targeting this key area, our approach aims to refine diagnostic precision and contribute to more effective treatment strategies for those at risk of vision loss.

GLAICOMA

Introduction & Background

  • Glaucoma is the leading cause of irreversible blindness in the world and is responsible for 12.8% of blindness in India and 15% in Africa.

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  • Glaucoma often causes vision loss without the patient noticing, particularly in elderly individuals who may mistakenly believe their declining vision is a natural part of aging.

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  • By 2040, an estimated 22 million people globally will be blind due to glaucoma.

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  • Though vision loss from glaucoma is gradual, progressive, and cannot be reversed, it can be managed with proper treatment.​ Early detection and treatment can prevent the progression of the
    disease.

Glaucoma blindness is preventable.

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RNFL

Studies show significant reduction of RNFL may occur prior to visual field loss, which could be useful in the early diagnosis of glaucoma.

DEEP LEARNING

Deep learning algorithms using OCT RNFL Thickness maps can aid in the early detection and diagnosis of glaucoma.

OCT

Experienced glaucoma specialists are needed to interpret OCT results, which is time-consuming and labor-intensive.

SCREENING

Such work could enhance our ability to use OCT as a screening tool for glaucoma in the future.

SOCIOECONOMICS

Accurate screening and proper surveillance are essential to decrease the socioeconomic burden of patients suffering from glaucoma.

GAP

To date, there is a lack of high-efficiency glaucoma diagnostic tools based on RNFL thickness maps.

PUB
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